Defiance is a third-person MMO shooter that Trion Worlds launched in 2013 alongside the Syfy series of the same name. It is set in the San Francisco Bay Area on an Earth reshaped by alien terraforming after a war between humans and alien arrivals.

You play an Ark Hunter chasing alien technology. The open world's headline events are Arkfalls: debris crashes down and dozens of players team up against monsters and large bosses. EGO implants grant abilities such as cloaking, overcharge and decoys, and you build loadouts from weapons, mods, shields and grenades. There are co-op missions and Shadow War PvP.

The servers closed in April 2021, but Fawkes Games relaunched the original game on PC through its own launcher in April 2025, with all five DLCs free. The graphics are dated, and updates so far mostly fix bugs.